Romeu concedes a corner at the death and Henderson comes up to meet the corner, but he can't direct his header anywhere near the target.
FULL-TIME: Sheffield United 0-1 Southampton
90' +4
CHANCE! Fleck whips his cross towards the back post from the right and Gunn failed to claim the floating delivery, which means it nearly sneaks into the back of the net but eventually drifts wide.
90' +2
S. Long enters the game and replaces C. Adams.
Southampton's final change sees Long replace Adams.
90'
There will be six minutes of added time.
89'
Henderson collects the ball and looks to thump it forward, but the Southampton defence are holding strong as they now look to crowd out Baldock on the right flank.
87'
Southampton are now happy to slow the game down as we reach the final stages, and that dismissal appears to have blunted the Blades' late attacking effort.
85'
B. Sharp goes off after a red card!
S. Armstrong enters the game and replaces S. Boufal.
Southampton make their second substitution as Armstrong replaces Boufal.
RED CARD! Sharp is dismissed for a lunging challenge on Armstrong with his studs up. The striker is complaining about the decision, but referee Lee Mason is not changing his mind.
84'
C. Robinson enters the game and replaces C. Basham.
Wilder adds another attacking option to his side with Robinson replacing Basham in the final United change.
82'
Fleck launches a long ball forward as United look to hit their opponents on the counter-attack with Mousset running at goal, but he sees his effort blocked from a tight angle and wins his side a corner.
80'
CHANCE! The Blades go close to levelling the scores as McGoldrick attacks Sharp's ball from the right with intent, but his effort is blocked by the Southampton defence and the danger is cleared after a series of United half-chances.
Minute
Description
77'
Ward-Prowse whips his corner deep into the box and towards the head of Vestergaard, but Basham makes a crucial intervention to clear the danger.
75'
The hosts are protesting that Ward-Prowse handled the ball in the box, but nothing is given and the referee waves play on as normal.
74'
D. Ings enters the game and replaces M. Djenepo.
Sharp glides past Vestergaard on the right flank and the striker then cuts the ball back for Basham, but the defender gets his feet in a tangle and he fails to execute a meaningful effort at goal.
Southampton's first change sees goalscorer Djenepo withdrawn, and he will be replaced by Ings.
72'
L. Mousset enters the game and replaces J. Lundstram.
The second substitution is a tactical switch which sees Lundstram make way for another striker in Mousset.
O'Connell claims possession deep in the Blades' half and he looks to pick out a pass to Sharp on the counter-attack, but his ball forward is cut out and the attack is quashed.
68'
That goal will have come as a crushing blow to the home side, who thought they had taken the lead earlier in the second half. Southampton are now the side in the ascendency as they look to create another opening in the final third.
66'
M. Djenepo has scored a goal for Southampton! Assist by S. Boufal.
WHAT A GOAL! It's an incredible solo goal from Djenepo who dances his way past four United players to get himself into space in the box, and he produces a measured finish from close range to bury the ball past Henderson.
That goal was all about Djenepo, but the role of Boufal in Southampton's lead should not be ignored as he regained possession in midfield to set Djenepo up for the run.
65'
J. Fleck gets yellow.
B. Sharp enters the game and replaces O. McBurnie.
McBurnie is replaced by Sharp in the first substitution of the day.
Fleck is booked for a late challenge on Adams as he nudges the striker off the ball.
64'
Djenepo does well to dance his way into some space on the edge of the United box, but his mazing run means he can't generate enough power behind his eventual effort and it's an easy save for Henderson.
63'
Some fine Southampton build-up play sees Boufal receive the ball on the edge of the box and he drops his shoulder before looking to curl his effort into the top left-hand corner, but it's sailing well over the bar.
61'
Henderson is forced to deal with a tricky ball into the United box, but he gets down low to claim it and immediately looks to launch a counter.
59'
Boufal slides a pall towards Djenepo on the right-hand side of the penalty area, but he loses his footing at a pivotal moment and it goes out for a goal-kick.
55'
The atmosphere understandably changed completely following that decision, with the VAR call muting the Blades' fans. Southampton are now back in possession and looking to move the ball between the lines.
53'
GOOOAL! McBurnie makes it 1-0 to the Blades after tapping home at the back post, but it's going through a video referee check...
51'
J. Vestergaard gets yellow.
Vestergaard is shown the first yellow card of the match for a late challenge on Baldock near the right-hand side touchline.
50'
Boufal picks up the ball some 30 yards from goal and weighs up his options before chipping a neat ball over the top to Adams, but Henderson emerges from his goal and beats the striker to the loose ball.
48'
A late challenge from Hojbjerg catches McGoldrick and the referee awards a free-kick, but the Blades are not happy about that challenge at all.
46'
The referee blows his whistle and we are back underway.
45' +1
HALF-TIME: Sheffield United 0-0 Southampton
45'
There will be one minute of added time in the first half.
44'
McBurnie is now back on his feet and will continue leading the Blades' line.
42'
Egan's foul on Boufal wins Southampton a free-kick inside the United half, but Ward-Prowse's delivery is not quite good enough and the hosts are now looking to launch a quick break.
40'
The dynamic of the match is starting to change slightly after Southampton's early authority, as the Blades are now looking much more comfortable in possession after a string of decent chances.
38'
Boufal is muscled away by Norwood as he makes a surging run down the left wing, but Lundstram manages to get back to force it out for a throw-in before Boufal can threaten further.
34'
Lundstram gets into a promising position on the right flank, but his delivery does not beat the first man and he fails to capitalise on the space he was permitted.
32'
A wonderful ball from Lundstram picks out Baldock as he surges into the box, but his first touch lets him down after getting past Vestergaard. Baldock is having plenty of joy in forward positions so far.
30'
Djenepo inadvertently puts the ball out for a Blades' corner, but the hosts cannot make the most of the opportunity despite Gunn's uncertainty in claiming the ball.
28'
Hojbjerg looks like he will be able to shake off his injury and continue.
24'
Southampton win a corner on the right-hand side which sees Vestergaard move forward to use his height in the box, but Ward-Prowse fails to get it past the first man.
22'
CHANCE! Ward-Prowse slides a neat through ball into the direction of Adams and Soares at the back post, and it eventually falls to Soares to have an effort at goal but he fires wide from close range.
20'
Fleck capitalises on Vestergaard's sloppy defending to break into the box from the right and looks to curl in a shot from a tight angle, but he gets it wrong and fires into the side-netting,
19'
Baldock gets into a good position in the Southampton box to meet Lundstram's long ball, but he takes too long to assess his options and Djenepo gets back to put it out for a corner.
17'
Fleck arrives in the box to meet a well-timed delivery from the right, but his header sails well over the bar and does not trouble Gunn one bit.
15'
After two major chances in quick succession, Southampton are looking to slow things down again as they casually pass the ball around the defence for a spell.
11'
Egan's header sees United concede a corner, but Vestergaard cannot get enough behind his header following Ward-Prowse's delivery.
7'
Some good build-up play from the home side allows Fleck time with the ball on the left flank and he manages to earn his side a corner, but it eventually comes to nothing as Southampton get the ball clear.
5'
Boufal's misplaced pass gives the Blades their first real spell of possession, but they fail to make much use of it as McBurnie is pushed to the ground when trying to get on the ball.
3'
Ward-Prowse wins a free-kick for Southampton following O'Connell's strong challenge, but Boufal's resulting delivery into the box is easily cleared away by the hosts.
1'
The referee blows his whistle and Southampton get us underway!
Hello and welcome to LIVE coverage of this Premier League clash between Sheffield United and Southampton!
SUBS: Luke Freeman, Callum Robinson, Simon Moore, Lys Mousset, Ben Osborn, Billy Sharp, Muhamed Besic.
SHEFFIELD UNITED (3-5-2): Dean Henderson; Chris Basham, John Egan, Jack O’Connell; George Baldock, John Lundstram, Oliver Norwood, John Fleck, Enda Stevens; David McGoldrick, Oli McBurnie.
Sheffield United have made a solid start to their Premier League return, winning once and drawing once in their four opening matches. Chris Wilder’s side currently sit 10th in the table and are looking for their second home league success of the season after seeing off Crystal Palace back in August.
Southampton are also starting to find some form in the top flight as they look to extend their unbeaten run to three games when they face the Blades. The south-coast side battled to a 1-1 draw against Manchester United before the international break, despite being reduced to ten men following Kevin Danso's second-half dismissal.
SUBS: Shane Long, Danny Ings, Ryan Bertrand, Yan Valery, Alex McCarthy, Stuart Armstrong, Jack Stephens.
SOUTHAMPTON (3-4-2-1): Angus Gunn; Maya Yoshida, Jannik Vestergaard, Jan Bednarek; Cedric Soares, Oriol Romeu, Pierre-Emile Hojbjerg; Moussa Djenepo; James Ward-Prowse, Sofiane Boufal; Che Adams.
The two sides have emerged from the tunnel and we are now very close to kick-off at Bramall Lane.
The players are re-emerging from the Bramall Lane tunnel and we are now nearing the restart.
It's a disappointing result for Sheffield United, who must now look to bounce back when they travel to face Everton next weekend, while Southampton will look to continue their fine run of form against Bournemouth.
That's all from Bramall Lane. Thank you for following live coverage of this Premier League clash!
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