Bruno Guimarães enters the game and replaces Douglas Luiz.
Lucas Paquetá enters the game and replaces Éverton Ribeiro.
Lucas Paqueta replaces Ribeiro as Brazil make a late change.
And it will be a very short Selecao debut Bruno Guimarees, who wins his first cap in these closing stages as he replaces Douglas Luiz.
90' +1
Marquinhos gets yellow.
Marquinhos picks up a late booking for a robust challenge now, though the Uruguay free-kick on the left flank comes to nothing.
90'
There's going to be four added minutes before this game is wrapped up.
89'
These sides won't be back on the World Cup trail until the end of March, over four months away. They'll have time to tweak what they need to - but Brazil, on this basis, probably won't have too much to deal with.
87'
Brazil are closing this out with an assured confidence across their midfield. They have refused to sit back too deep this half, and allow Uruguay to find a serious second wind. They've tried to keep the ball around that middle third, on the cusp of a breakaway; it has kept the hosts on their toes, straining for clear-cut chances of their own.
85'
M. Cáceres gets yellow.
Caceres is the latest Uruguay man to draw a yellow card from the referee after he crashes into a free-running Lodi out on the wing.
84'
We've had 26 fouls in this game. Honestly, it feels like it could be twice as many as that. It's been a spirited game turned particularly pugilistic in a sense as it has worn on.
82'
Nunez is still flying solo up front for the hosts but the service is about as decent as that from a rickety television aerial right now, cut out by the Brazil defence.
80'
Uruguay will hope that they can look back on this game of arguable fine margins in two years and four days - the date of the opening game in Qatar, of course - and laugh about it, but it is certainly no joking matter in the here and now. A man and two goals down is not what they had hoped for today.
Minute
Description
78'
Two tough calls against Uruguay in the space of five minutes. It's no wonder they are getting quite agitated. Brazil have outgunned them in this second half though and that was the closest they've come to pulling something back. The clock continues to tick away.
76'
J. Rodríguez gets yellow.
Goal! Wait, no goal! Uruguay think they have pulled one back but the flag is up for offside. Players bundle into the referee, who is naturally less than impressed at being manhandled by a group of angry footballers and promptly shows a yellow to Rodriguez.
73'
Everyone will have their opinion on that, but it feels like a harsh call. A yellow card is definitely suitable but a red? To the letter of the law the game goes however, no matter the protests of the Uruguay squad. On the touchline, Cavani is exchanging heated words with officials. The hosts are absolutely furious.
71'
E. Cavani goes off after a red card!
Hang on, the referee is going over to VAR to have a look at this Cavani challenge - and it is a red card for the striker! Uruguay are down to 10 men! The Manchester United man cannot believe it. His booking is overturned and promptly upgraded to a sending-off.
70'
J. Rodríguez enters the game and replaces N. de la Cruz.
Everton enters the game and replaces Richarlison.
It will actually be Richarlison's last act, as he makes way for Everton Soares in the latest Brazil change.
Uruguay meanwhile introduce Jonathan Rodriguez for De La Cruz.
69'
Cavani comes in on Richarlison now and picks up a reprimand for his troubles. It looks like it might be a stamp on the Everton man, but if so, it appears to be accidental.
67'
N. Nández gets yellow.
Nandez clatters in on Arthur now and gets duly booked for his troubles.
66'
Cavani and Nunez are still making those runs though, even if service isn't quite as reliable this half. Time is running out for them to make something of it though.
64'
Brazil have definitely done their part in slowing down the Uruguay attack since the break, but whether a sizeable chunk of that comes from the hosts simply running out of juice is another matter. They were absolutely relentless on-and-off the ball in that first half-hour.
60'
M. Arambarri enters the game and replaces L. Torreira.
B. Rodríguez enters the game and replaces R. Bentancur.
The hosts also introduce Brian Rodriguez in place of Bentancur.
Uruguay make their first change of the game now as Mauro Arambarri replaces Torreira.
59'
Richarlison gets yellow.
Richarlison bulldozes De La Cruz on the wing now and picks up a booking for his efforts. The referee came close to drawing the red card there, but settles on a yellow in the end, which is the right call.
58'
Uruguay's latest corner down the other end is a busted flush of a delivery which Brazil have no trouble batting away. They need a little more grunt in the final third, or at least a major defensive error to go their way.
56'
Lodi now spearheads a swift Brazil move down the left flank and Campana is forced to make a diving save to collect a square pass whipped across the six-yard area.
55'
It really goes without saying but a goal for Uruguay here would lift the spirits of both them and this game immensely. The energy levels aren't quite there following the break, but a response from the hosts could set this tie alight once again.
53'
Now it is Uruguay's turn to draw the free-kick, albeit deep in midfield as Torreira clutches his face coming down from a high challenge.
51'
J. Giménez gets yellow.
Gimenez is booked for that challenge too, but he hasn't delivered a third goal to the visitors in the end; the set-piece swings straight into the hands of Campana.
50'
An early Uruguay corner here comes to nothing when a Brazil man is deemed to have been dragged down in the box and then Gimenez tracks down Gabriel Jesus on the edge of his own box following a swift counter-move. This is dangerous free-kick territory for the hosts to concede.
48'
There's been no changes at the break, but don't be too surprised if one side introduces some fresh legs into the equation sooner rather than later. The Selecao will have to decide whether they want to sit back on this one and invite Uruguay in or go on the attack themselves.
46'
We're back underway for the second half in Montevideo. Can Uruguay find a way back into this tie on the scoreboard or will it be plain sailing for Brazil from here on out?
45' +4
HALF-TIME: URUGUAY 0-2 BRAZIL
45' +3
Douglas Luiz gets yellow.
At last, the first yellow card of the game comes out, and it's for Douglas Luiz, with a sketchy challenge out on the left wing. This free-kick will be in box delivery territory for Uruguay...
45' +1
We're going to have three added minutes before the break here. Uruguay have a mountain to climb now.
45'
Richarlison has scored a goal for Brazil! Assist by Renan Lodi.
It's a lovely first-touch delivery from the Brazil left-back there, clipped acorss with a wonderful weight. Training ground stuff, you may say, but the finish is a good one.
GOAL! RICHARLISON DOUBLES BRAZIL'S LEAD! 2-0! Have the visitors killed this game off on the stroke of half-time? The set-piece is played short and finds Lodi on the left wing to volley a delivery across the box - and the Everton man, shrugging off any marker he had, rises, to plant a header past Campana at the right post. A hammer-blow from the Selecao!
44'
Gimenez mistimes a touch in attempting to clear a Brazil delivery and the Selecao will have a corner as this first half rumbles towards a close.
42'
As if on cue, Ribeiro is promptly tripped with a particularly ragged effort. No booking comes Uruguay's way and the ball is far enough away from any danger area to seriously trouble Campana and the hosts' defence.
40'
There appears to have been a slight dial-down in the intensity of challenges over the last few minutes too. There were no cards early on, but certainly a few efforts termed as "robust" were skirting the letter of the law. The energy seems to be going into high presses and other fast tactics right now.
38'
There's still very little between these two sides and in terms of ball movement, you'd probably still say that the hosts are shading it. But it is a significant task, physically and mentally, to come back from a goal down against Brazil for any side. This will require Uruguay's sternest stuff.
36'
That is a blow to Uruguay, who have mounted some sustained pressure in this match for no show in the end there. They almost go further behind after Firmino slips two defenders and embarks on a brazen run, just pushing his finish straight to the keeper in the end.
34'
Arthur has scored a goal for Brazil! Assist by Gabriel Jesus.
GOAL! ARTHUR SNATCHES THE OPENER FOR BRAZIL! 1-0! Arguably against the run of play, the Selecao have got themselves ahead on the scoresheet! A cross into the box from that right wing isn't cleared away by Uruguay and it falls to the midfielder outside it. He takes two steps right around the nearest defender and lofts an effort through the crowd of players, with a kind deflection taking it away from Campana and in at the left post. First blood to the visitors.
Gabriel Jesus is the man to have played the ball back there, rather than a failed Uruguay clearance. It's lovely work from the Manchester City man, unbowed under pressure there.
32'
Having been stymied in their attacks, Brazil are finding their feet again going forward now, running a sharp line down the right wing once again. They look a little more threatening on the front foot.
29'
Thiago Silva heads a Nandez ball out for a corner and Uruguay play it short, looking to build an attack rather than swing it in. They're met with stern resistance; a half-hearted shout for a penalty is waved away and Brazil manage to force the visitors back to midfield.
27'
Ederson kills some time around his box with the ball at his feet, almost daring Nunez to come and have a bite. He picks it up before the Uruguay man can take him up on his offer for a shot at goal, with the forward darting in keenly.
23'
Richarlison attempts an impressive double somersault to convince the referee that Bentancur fouled him near the centre-circle but the Uruguay man came away with the ball cleanly. The Everton striker gets nothing except some admiration for his gymnastics.
21'
It's a soft set-piece from the hosts, but Brazil don't press possession back to midfield with great success and Uruguay come again, working their way neatly down the left wing until Nunez' tight throughball skims itself over the touchline for a Selecao throw-in.
19'
Cavani hustles after a neat lob cross that Thiago Silva is a moment too late to react to, but the striker slips in his pursuit and Douglas Luiz is able to smash out for a corner.
17'
Firmino and Gimenez get into a tussle as the Liverpool man roars forward down that right edge, having briefly swapped wings in attack. The ball squirts away from both and the linesman signals for a Uruguay throw-in.
15'
Bentancur puts Douglas Luiz on his backside with a late lunge that could perhaps be charitably described as "committed". It's a free-kick in midfield and nothing more.
13'
You can't accuse this match of being played at something of a sedate tempo. Never mind that this is the third international break in as many months, with a lot of these players figuring in a heavily accelerated European timetable; they are not letting this one slow down for anything.
11'
Over the crossbar! Cavani latches onto the end of a well-balanced cross on the cusp of Brazil's six-yard area and powers a header above and slightly wide of the woodwork. Close, but no coconut for the Manchester United man.
9'
It's a poor set-piece delivery from the visitors in the end but that does little to dissuade them of coming again. Gimenez is forced to work it out of his own rear third and then Uruguay counter smartly, with Ederson required to race out to the edge of his box to snatch up a wayward deflection that almost falls kindly for a lurking Cavani.
7'
This has been a spirited set of early exchanges and now Brazil draw a dangerous free-kick 25 yards out in the right edge, after a high challenge from Cavani catches Douglas Luiz with an errant boot.
4'
Indeed, Jesus is causing enough trouble with those balls to warrant a stop from Campana, who flicks a glove onto one such delivery that veers perilously close to his goal-line.
3'
Both sides make early incursions, but it is the Selecao who work their advantages early, travelling down the right flank through Danilo and Gabriel Jesus, pinging a couple of speculative crosses in.
1'
We are underway in this FIFA World Cup qualifier between Uruguay and Brazil!
Hello and welcome to live coverage of the CONMEBOL qualifiers for the 2022 FIFA World Cup, as leaders Brazil make the trip south to face Uruguay at Estadio Centenario in Montevideo.
Several nations around the world may have not started their engines yet, but the road to Qatar is well underway in South America, as their 10 nations gear up for matchday four on their long journey to make it to the Middle East. Half of the continent's sides played their part in Russia in 2018, but none made it to the last four - and plenty of nations will be out to change their fortunes this time out.
Uruguay and Brazil, of course, were the two that got closest; if they had managed to get the better of eventual champions France and third-placed Belgium respectively in the quarter-finals, they would have contested a semi-final encounter themselves. Instead, they now have their eyes on the new prize of lifting football's greatest prize in Lusail in just over two years - and a win for either today would help throw down a marker.
It's been the perfect start to this campaign for Tite's side, with three wins from three for the Selecao including a 4-2 triumph over fellow 2018 contenders Peru. Uruguay have slipped up once, in an upset to Ecuador - but wins either side of that defeat means they aren't too far off the pace either. This is both teams' biggest test yet though, and they know it.
There's four Atletico Madrid men across both sides today, while there's a clutch of faces from current Premier League champions Liverpool and their local rivals Everton. The weather is probably a little colder back on Merseyside right now than in Uruguay, one would imagine...
Tite will likely be quite pleased with how that first half worked out in the end. When his side were under the cosh, they stood firm and then went and promptly bagged two goals down the other end. As plenty of teams will attest to, that's very much part of the mettle of champions.
Four games, four wins. It's far from confirmed, with 14 more to go, but you'd feel pretty confident about stamping Brazil's passport to Qatar. The 2014 hosts are surely heading to another World Cup - and they may hope to repeat France's feat from two years ago, and claim another triumph 20 years after their last one. Once they confirm their spot, expect Tite to give fringe players a chance; he will want the best spread possible for his latest crack at silverware.
It's a long wait now - four months and a week - but both Uruguay and Brazil will be back for matchday 5 next year on March 25. Both sides will be on the road; Uruguay face the daunting task of a trip to Argentina, while Brazil will head to fellow World Cup vets Colombia. Until then though, thank you for joining us - and have a good week!
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